Definition and treatment of lupus flares measured by the BILAG index

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Definition and treatment of lupus flares measured by the BILAG index.

OBJECTIVES The BILAG index is a clinical measure of lupus disease activity. It is valid, reliable and sensitive to change. Scoring in the BILAG index is based upon the physician's intention to treat. A flare of active lupus is defined as a new A or B score in at least one system. The main aim of this study was to determine whether patients with a lupus flare are treated as expected from the pri...

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How should lupus flares be measured? Deconstruction of the safety of estrogen in lupus erythematosus national assessment-systemic lupus erythematosus disease activity index flare index.

OBJECTIVE Accurate assessment of lupus flares is critical but problematic in clinical trials. This study examined the impact of modifications to the classic Safety of Estrogens in Lupus Erythematosus National Assessment (SELENA)-SLEDAI flare index (cSFI). METHODS Ninety-one SLE patient records were evaluated at two visits at which the SLEDAI and BILAG had been scored prospectively. The cSFI w...

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Numerical scoring for the BILAG-2004 index

OBJECTIVE To develop an additive numerical scoring scheme for the BILAG-2004 index. METHODS SLE patients were recruited into this multi-centre cross-sectional study. At every assessment, data were collected on disease activity and therapy. Logistic regression was used to model an increase in therapy, as an indicator of active disease, by the BILAG-2004 index score in the nine systems. As both...

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Numerical scoring for the Classic BILAG index

OBJECTIVE To develop an additive numerical scoring scheme for the Classic BILAG index. METHODS SLE patients were recruited into this multi-centre cross-sectional study. At every assessment, data were collected on disease activity and therapy. Logistic regression was used to model an increase in therapy, as an indicator of active disease, by the Classic BILAG score in eight systems. As both in...

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ژورنال

عنوان ژورنال: Rheumatology

سال: 2003

ISSN: 1460-2172

DOI: 10.1093/rheumatology/keg382